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Massimo Breccia Selected Research

ruxolitinib

6/2022Safety and effectiveness of ruxolitinib in the real-world management of polycythemia vera patients: a collaborative retrospective study by pH-negative MPN latial group.
1/2022Deferasirox in the management of iron overload in patients with myelofibrosis treated with ruxolitinib: The multicentre retrospective RUX-IOL study.
1/2022RR6 prognostic model provides information about survival for myelofibrosis treated with ruxolitinib: validation in a real-life cohort.
1/2022Peripheral blasts are associated with responses to ruxolitinib and outcomes in patients with chronic-phase myelofibrosis.
1/2022Adherence to ruxolitinib, an oral JAK1/2 inhibitor, in patients with myelofibrosis: interim analysis from an Italian, prospective cohort study (ROMEI).
9/2021Philadelphia-Negative Chronic Myeloproliferative Neoplasms during the COVID-19 Pandemic: Challenges and Future Scenarios.
8/2021Management of myelofibrosis and concomitant advanced cutaneous squamous cell carcinoma with ruxolitinib associated with cemiplimab.
1/2021Ruxolitinib discontinuation syndrome: incidence, risk factors, and management in 251 patients with myelofibrosis.
1/2021Second primary malignancy in myelofibrosis patients treated with ruxolitinib.
1/2021Ruxolitinib rechallenge in resistant or intolerant patients with myelofibrosis: Frequency, therapeutic effects, and impact on outcome.
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Massimo Breccia Research Topics

Disease

156BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
11/2022 - 04/2004
31Primary Myelofibrosis (Myelosclerosis)
06/2022 - 10/2004
31Myelodysplastic Syndromes (Myelodysplastic Syndrome)
05/2022 - 01/2002
30Acute Promyelocytic Leukemia
11/2021 - 02/2002
28Neoplasms (Cancer)
11/2022 - 01/2002
19Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2022 - 01/2002
14Blast Crisis (Blast Phase)
11/2021 - 04/2004
14Philadelphia Chromosome
01/2021 - 09/2006
13Leukemia
10/2022 - 11/2004
11Infections
01/2022 - 08/2003
9Splenomegaly
01/2022 - 01/2016
9Anemia
01/2021 - 06/2010
8Hematologic Neoplasms (Hematological Malignancy)
10/2020 - 02/2002
6Chromosome Aberrations (Chromosome Abnormalities)
11/2017 - 01/2009
6Pathologic Complete Response
09/2011 - 02/2002
5Fatigue
06/2022 - 10/2014
5Iron Overload
01/2022 - 07/2013
5Residual Neoplasm
01/2022 - 09/2003
5Pleural Effusion (Pleural Effusions)
11/2021 - 09/2010
5Thrombosis (Thrombus)
08/2021 - 09/2015
5Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
04/2013 - 08/2012
4Thrombocytopenia (Thrombopenia)
01/2021 - 02/2018
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2013 - 10/2008
3Polycythemia Vera
06/2022 - 10/2018
3Myeloid Leukemia (Leukemia, Myelocytic)
12/2020 - 08/2016
3Hypertension (High Blood Pressure)
07/2020 - 03/2015
3Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 05/2008
3Exanthema (Rash)
10/2014 - 05/2011
2Chronic Disease (Chronic Diseases)
06/2022 - 02/2015
2Sepsis (Septicemia)
05/2022 - 11/2015
2COVID-19
09/2021 - 06/2021
2Venous Thromboembolism
01/2021 - 10/2020
2Thrombocytosis (Thrombocythemia)
01/2021 - 01/2008
2Atrial Fibrillation
12/2020 - 10/2020
2Frailty
11/2020 - 05/2018
2Hemorrhage
10/2020 - 03/2009
2Essential Thrombocythemia
09/2020 - 10/2018
2Obesity
01/2020 - 03/2015
2Pancreatitis
12/2019 - 12/2009
2Multiple Myeloma
12/2019 - 04/2012
2Genetic Translocation (Chromosomal Translocation)
01/2018 - 01/2015
2Fibrosis (Cirrhosis)
02/2017 - 11/2014
2Type 2 Diabetes Mellitus (MODY)
07/2015 - 04/2012
2Cytopenia
12/2012 - 08/2012
2Non-Hodgkin Lymphoma (Lymphosarcoma)
10/2011 - 02/2008
2Myeloproliferative Disorders (Myeloproliferative Disorder)
07/2009 - 11/2005
2Disease Progression
10/2004 - 08/2003
1Fever (Fevers)
05/2022
1Bacteremia
05/2022

Drug/Important Bio-Agent (IBA)

92Imatinib Mesylate (Gleevec)FDA Link
01/2021 - 04/2004
75Tyrosine Kinase InhibitorsIBA
11/2022 - 12/2008
31ruxolitinibIBA
06/2022 - 11/2014
25nilotinibFDA Link
10/2022 - 01/2007
24Dasatinib (BMS 354825)FDA Link
11/2021 - 01/2007
20Tretinoin (Retinoic Acid)FDA LinkGeneric
11/2021 - 02/2002
19Pharmaceutical PreparationsIBA
10/2020 - 03/2006
16Azacitidine (5 Azacytidine)FDA Link
10/2020 - 10/2011
12Arsenic Trioxide (Trisenox)FDA Link
11/2021 - 05/2004
11ponatinibIBA
01/2021 - 01/2016
10Biological ProductsIBA
05/2022 - 08/2003
10DeferasiroxFDA Link
01/2022 - 09/2012
10Phosphotransferases (Kinase)IBA
12/2020 - 10/2008
7Lenalidomide (CC 5013)FDA Link
03/2015 - 09/2010
6IronIBA
01/2017 - 09/2012
5InterferonsIBA
09/2021 - 01/2011
5AnticoagulantsIBA
01/2021 - 11/2005
5Interferon-alpha (Interferon Alfa)IBA
01/2016 - 02/2008
4bosutinibIBA
08/2021 - 01/2015
4ErythropoietinFDA Link
09/2020 - 08/2014
4AnthracyclinesIBA
12/2019 - 02/2011
4Gemtuzumab (Mylotarg)FDA Link
02/2011 - 10/2004
3amsonic acid (DAS)IBA
11/2021 - 01/2016
3Hydroxyurea (Hydrea)FDA LinkGeneric
09/2021 - 01/2012
3Ferritins (Ferritin)IBA
08/2020 - 07/2013
3Glucose (Dextrose)FDA LinkGeneric
11/2012 - 05/2010
2LDL Lipoproteins (beta Lipoproteins)IBA
08/2021 - 01/2020
2asciminibIBA
08/2021 - 12/2019
2Therapeutic UsesIBA
01/2021 - 04/2018
2CytokinesIBA
10/2020 - 02/2002
2Lipase (Acid Lipase)FDA Link
12/2019 - 12/2009
2Chelating AgentsIBA
07/2015 - 07/2013
2Hemoglobins (Hemoglobin)IBA
05/2015 - 03/2015
2NF-kappa B (NF-kB)IBA
07/2013 - 04/2011
2Amphotericin B (Amphotericin)FDA LinkGeneric
04/2012 - 04/2004
2Bortezomib (Velcade)FDA Link
04/2012 - 04/2011
2Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
10/2010 - 12/2008
1Core Binding Factors (Core-Binding Factor)IBA
10/2022
1Dihydroorotate DehydrogenaseIBA
06/2022
1ProcalcitoninIBA
05/2022
1C-Reactive ProteinIBA
05/2022

Therapy/Procedure

84Therapeutics
11/2022 - 01/2002
22Drug Therapy (Chemotherapy)
10/2022 - 02/2002
5Stem Cell Transplantation
10/2022 - 03/2003
4Salvage Therapy
01/2020 - 11/2010
3Chelation Therapy (Therapy, Chelation)
10/2015 - 09/2012
2Polypharmacy
11/2020 - 11/2016
2Homologous Transplantation
01/2020 - 01/2010
2Duration of Therapy
04/2013 - 05/2009
2Palliative Care (Palliative Therapy)
03/2009 - 05/2007
1Patient Admission (Patient Admissions)
05/2022